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Recent Publications

Publications

2017
Ben-Nun Y, G, Fichman , L, Adler-Abramovich , B, Turk , E, Gazit , and G, Blum . 7/10/2017. “Cathepsin Nanofiber Substrates As Potential Agents For Targeted Drug Delivery”. J Control Release., 257, Pp. 60-67. . Publisher's Version
Amit U, D, Kain , A, Wagner , A, Sahu , Y, Nevo-Caspi , N, Gonen , N, Molotski , T, Konfino , N, Landa , N, Naftali-Shani , G, Blum , E, Merquiol , D, Karo-Atar , Y, Kanfi , G, Paret , A, Munitz , HY, Cohen , E, Ruppin , S, Hannenhalli , and J, Leor . 5/20/2017. “A New Role For Interleukin-13 Receptor Α1 In Myocardial Homeostasis And Heart Failure”. J Am Heart Assoc. . Publisher's Version
Tommy Weiss-Sadan, Gotsman, Israel , and Blum, Galia . 2/16/2017. “Cysteine Proteases In Atherosclerosis”. Febs J ., 284, 10, Pp. 1455-1472. . Publisher's Version
Barkan Y, M, Levinman , I, Veprinsky-Zuzuliya , T, Tsach , E, Merqioul , G, Blum , AJ, Domb , and A, Basu . 1/15/2017. “Comparative Evaluation Of Polycyanoacrylates”. Acta Biomater., 48, Pp. 390-400. . Publisher's Version
2016
Dror Alishekevitz, Gingis-Velitski, Svetlana , Kaidar-Person, Orit , Gutter-Kapon, Lilach , Scherer, Sandra D. , Raviv, Ziv , Merquiol, Emmanuelle , Ben-Nun, Yael , Miller, Valeria , Rachman-Tzemah, Chen , Timaner, Michael , Mumblat, Yelena , Ilan, Neta , Loven, David , Hershkovitz, Dov , Satchi-Fainaro, Ronit , Blum, Galia , Sleeman, Jonathan P. , Vlodavsky, Israel , and Shaked, Yuval . 10/25/2016. “Macrophage-Induced Lymphangiogenesis And Metastasis Following Paclitaxel Chemotherapy Is Regulated By Vegfr3”. Cell Rep., 17, 5, Pp. 1344–1356. . Publisher's Version
Abd-Elrahman I, H, Kosuge , T, Wises Sadan , Y, Ben-Nun , K, Meir , C, Rubinstein , M, Bogyo , MV, McConnell , and G, Blum . 8/17/2016. “Cathepsin Activity-Based Probes And Inhibitor For Preclinical Atherosclerosis Imaging And Macrophage Depletion”. Plos One., 11, 8. . Publisher's Version
Abd-Elrahman I, K, Meir , H, Kosuge , Y, Ben-Nun , T, Weiss Sadan , C, Rubinstein , Y, Samet , MV, McConnell , and G, Blum . 3/3/2016. “Characterizing Cathepsin Activity And Macrophage Subtypes In Excised Human Carotid Plaques”. Stroke, 47, 4, Pp. 1101-1108. . Publisher's Version
Abu-Fanne R, E, Maraga , I, Abd-Elrahman , A, Hankin , G, Blum , S, Abdeen , N, Hijazi , DB, Cines , and AA, Higazi . 2/5/2016. “Α-Defensins Induce A Post-Translational Modification Of Low Density Lipoprotein (Ldl) That Promotes Atherosclerosis At Normal Levels Of Plasma Cholesterol.”. J Biol Chem., 291, 6, Pp. 2777-2786. . Publisher's Version
Shaulov-Rotem Y, E, Merquiol , T, Weiss-Sadan , O, Moshel , S, Salpeter , D, Shabat , F, Kaschani , M, Kaiser , and G, Blum . 2/1/2016. “A Novel Quenched Fluorescent Activity-Based Probe Reveals Caspase-3 Activity In The Endoplasmic Reticulum During Apoptosis”. Chem Sci., 7, 2, Pp. 1322-1337. . Publisher's Version
2015
Ben-Nun Y, E, Merquiol , A, Brandis , B, Turk , A, Scherz , and G, Blum . 4/27/2015. “Photodynamic Quenched Cathepsin Activity Based Probes For Cancer Detection And Macrophage Targeted Therapy”. Theranostics., 5, 8, Pp. 847-862. . Publisher's Version
Salpeter SJ, Y, Pozniak , E, Merquiol , Y, Ben-Nun , T, Geiger , and G, Blum . 3/23/2015. “A Novel Cysteine Cathepsin Inhibitor Yields Macrophage Cell Death And Mammary Tumor Regression”. Oncogene., 34, Pp. 6066–6078. . Publisher's Version
Ben-Aderet L, E, Merquiol , D, Fahham , D, Kumar , E, Reich , Y, Ben-Nun , L, Kandel , A, Haze , M, Liebergall , MK, Kosinska , J, Steinmeyer , B, Turk , and G, Blum . 3/20/2015. “Detecting Cathepsin Activity In Human Osteoarthritis Via Activity-Based Probes”. Arthritis Research & Therapy, 17, 69. . Publisher's Version
Riahi Y, N, Kaiser , G, Cohen , I, Abd-Elrahman , G, Blum , OM, Shapira , T, Koler , M, Simionescu , AV, Sima , N, Zarkovic , K, Zarkovic , M, Orioli , G, Aldini , E, Cerasi , G, Leibowitz , and S, Sasson . 3/5/2015. “ Foam Cell-Derived 4-Hydroxynonenal Induces Endothelial Cell Senescence In A Txnip-Dependent Manner”. J Cell Mol Med. , 19, 8, Pp. 1887-1899. . Publisher's Version
2013
Ben-Mordechai T, R, Holbova , N, Landa-Rouben , T, Harel-Adar , MS, Feinberg , I, Abd Elrahman , G, Blum , FH, Epstein , Z, Silman , S, Cohen , and J, Leor . 11/12/2013. “Macrophage Subpopulations Are Essential For Infarct Repair With And Without Stem Cell Therapy”. J Am Coll Cardiol., 62, 20, Pp. 1890-1901. . Publisher's Version
Rothberg JM, KM, Bailey , JW, Wojtkowiak , Y, Ben Nun , MS, Boygo , E, Weber , K, Moin , G, Blum , RR, Mattingly , RJ, Gillies , and BF, Sloane . 10/2013. “Acid-Mediated Tumor Proteolysis: Contribution Of Cysteine Cathepsins”. Neoplasia, 15, 10, Pp. 1125-1137. . Publisher's Version
Seth J.Salpeter and Blum, Galia . 2/21/2013. “Ready, Set, Cleave: Proteases In Action”. Chemistry & Biology, 20, 2, Pp. 168-176. . Publisher's Version
2012
Edgington LE, M, Verdoes , A, Ortega , NP, Withana , J, Lee , S, Syed , MH, Bachmann , G, Blum , and MPI, Bogyo . 12/8/2012. “Functional Imaging Of Legumain In Cancer Using A New Quenched Activity-Based Probe. ”. J Am Chem Soc., 135, 1, Pp. 174-182. . Publisher's Version
Verdoes M, LE, Edgington , FAS, Scheeren , M, Leyva , G, Blum , K, Weiskopf , MH, Bachmann , JAC, Ellman , and MPI, Bogyo . 5/25/2012. “A Nonpeptidic Cathepsin S Activity-Based Probe For Noninvasive Optical Imaging Of Tumor-Associated Macrophages. ”. Chem Biol. , 19, 5, Pp. 619-628. . Publisher's Version