Publications

2012

Cutter JL, NT, Cohen , J, Wang , AE, Sloan , AR, Cohen , A, Panneerselvam , M, Schluchter , G, Blum , M, Bogyo , and JP, Basilion . 3/13/2012. “Topical Application Of Activity-Based Probes For Visualization Of Brain Tumor Tissue. ”. Plos One., 7, 3. . Publisher's Version

Withana NP, G, Blum , M, Sameni , C, Slaney , A, Anbalagan , MB, Olive , BN, Bidwell , L, Edgington , L, Wang , K, Moin , BF, Sloane , RL, Anderson , MS, Bogyo , and BS, Parker . 3/1/2012. “ Cathepsin B Inhibition Limits Bone Metastasis In Breast Cancer”, 72, 5, Pp. 1199-1209. . Publisher's Version

2011

Ren G, G, Blum , M, Verdoes , H, Liu , S, Syed , O, Gheysens , Z, Miao , H, Jiang , SS, Gambhir , M, Bogyo , and Z, Cheng . 11/21/2011. “Non-Invasive Imaging Of Cysteine Cathepsin Activity In Solid Tumors Using A ⁶⁴Cu-Labeled Activity-Based Probe”. Plos One. . . Publisher's Version

Tedelind S, S, Jordans , H, Resemann , G, Blum , M, Bogyo , D, Führer , and K, Brix . 8/3/2011. “Cathepsin B Trafficking In Thyroid Carcinoma Cells”. Thyroid Res. . Publisher's Version

2009

Blum G, RM, Weimer , LE, Edgington , W, Adams , and M, Bogyo . 7/28/2009. “Comparative Assessment Of Substrate And Activity Based Probes As Tools For Non-Invasive Optical Imaging Of Cysteine Protease Activity”. Plos One., 4(7), Pp. e6374. . Publisher's Version

Edgington LE, AB, Berger , G, Blum , VE, Albrow , MG, Paulick , N, Lineberry , and M, Bogyo . 7/13/2009. “Non-Invasive Optical Imaging Of Apoptosis Using Caspase-Targeted Activity Based Probes”. Nat Med., 15, Pp. pages967–973. . Publisher's Version

Chang SH, K, Kanasaki , V, Gocheva , G, Blum , J, Harper , MA, Moses , SC, Shih , JA, Nagy , J, Joyce , M, Bogyo , R, Kalluri , and HF, Dvorak . 5/15/2009. “Vegf-A Induces Angiogenesis By Perturbing The Cathepsin-Cysteine Protease Inhibitor Balance In Venules Causing Basement Membrane Degradation, Mother Vessel Formation”. Cancer Res., 69, 10, Pp. 4537-4544. . Publisher's Version

Cavallo-Medved D, D, Rudy , G, Blum , M, Bogyo , D, Caglic , and BF, Sloane . 4/15/2009. “Live-Cell Imaging Demonstrates Extracellular Matrix Degradation In Association With Active Cathepsin B In Caveolae Of Endothelial Cells During Tube Formation”. Exp Cell Res., 315, 7, Pp. 1234-1246. . Publisher's Version

Yang Z, M, Fonović , SH, Verhelst , G, Blum , and M, Bogyo . 2/1/2009. “Evaluation Of Β-Unsaturated Ketone-Based Probes For Papain-Family Cysteine Proteases”. Bioorg Med Chem., 17, 3, Pp. 1071-1078. . Publisher's Version

2008

Galia Blum. 9/2008. “Use Of Fluorescent Imaging To Investigate Pathological Protease Activity”. Curr Opin Drug Discov Devel., 11, 5, Pp. 708-716. . Publisher's Version

Qvit N, H, Reuveni , S, Gazal , A, Zundelevich , G, Blum , MY, Niv , A, Feldstein , S, Meushar , DE, Shalev , A, Friedler , and C, Gilon . 2/14/2008. “Synthesis Of A Novel Macrocyclic Library: Discovery Of An Igf-1R Inhibitor”. J Comb Chem., 10, 2, Pp. 256-266. . Publisher's Version

2007

Blum G, von G, Degenfeld , MJ, Merchant , HM, Blau , and M, Bogyo . 9/9/2007. “Noninvasive Optical Imaging Of Cysteine Protease Activity Using Fluorescently Quenched Activity-Based Probes.”. Nat Chem Biol., 3, Pp. 668-677. https://www.nature.com/articles/nchembio.9/9/2007. 26. Publisher's Version

Steiner L, G, Blum , Y, Friedmann , and A, Levitzki . 5/7/2007. “Atp Non-Competitive Igf-1 Receptor Kinase Inhibitors As Lead Anti-Neoplastic Papilloma Agents”. Eur J Pharmacol, 562, 1-2, Pp. 1-11. . Publisher's Version

Sexton KB, MD, Witte , G, Blum , and M, Bogyo . 2/1/2007. “Design Of Cell-Permeable, Fluorescent Activity-Based Probes For The Lysosomal Cysteine Protease Asparaginyl Endopeptidase (Aep)/Legumain.”. Bioorg Med Chem Lett, 17, 3, Pp. 649-653. . Publisher's Version

2006

Yuan F, SH, Verhelst , G, Blum , LM, Coussens , and M, Bogyo . 5/3/2006. “A Selective Activity-Based Probe For The Papain Family Cysteine Protease Dipeptidyl Peptidase I/Cathepsin C”. J Am Chem Soc., 128, Pp. 5616-5617. . Publisher's Version

2005

Blum G, SR, Mullins , K, Keren , M, Fonovic , C, Jedeszko , MJ, Rice , BF, Sloane , and M, Bogyo . 8/14/2005. “Dynamic Imaging Of Protease Activity With Fluorescently Quenched Activity-Based Probes”. Nat Chem Biol., 1, Pp. 203-209. . Publisher's Version

Kato D, KM, Boatright , AB, Berger , T, Nazif , G, Blum , C, Ryan , KA., Chehade , GS, Salvesen , and M, Bogyo . 5/24/2005. “Activity-Based Probes That Target Diverse Cysteine Protease Families”. Nat Chem Biol., 1, Pp. 33-38. . Publisher's Version

2003

Blum G, A, Gazit , and A, Levitzki . 10/17/2003. “Development Of New Insulin-Like Growth Factor-1 Receptor Kinase Inhibitors Using Catechol Mimics”. J Biol Chem., 278, Pp. 40442-54. . Publisher's Version

2000

Blum G, A, Gazit , and A, Levitzki . 11/28/2000. “Substrate Competitive Inhibitors Of Igf-1 Receptor Kinase”. Biochemistry, 39, Pp. 15705-15712. . Publisher's Version

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